Voxel-Based Specific Regional Analysis System for Alzheimer's Disease (VSRAD) Test (Detect Early Signs of Alzheimer's)

· Those in Tokyo who want to screen for early signs of Alzheimer’s disease.
· Those who want to monitor brain atrophy using MRI-based analysis.
· Those who want to better understand their current brain health status.
· Those who wish to assess memory decline or cognitive changes.
· Those who wish to take preventive steps due to a family history of dementia.

VSRAD (Voxel-Based Specific Regional Analysis System for Alzheimer’s Disease) is a specialized diagnostic tool that uses MRI imaging to detect early signs of Alzheimer’s by analyzing brain atrophy. It focuses on key regions affected in the initial stages of the disease, such as the hippocampus, parahippocampal gyrus, and amygdala – areas responsible for memory and emotional processing.

This non-invasive test provides a detailed, visual, and quantitative assessment of brain volume loss, helping doctors identify subtle changes that may not be visible on standard imaging. By detecting potential abnormalities early, VSRAD allows for timely intervention, better monitoring of cognitive health, and improved support for patients at risk of dementia.

VSRAD (Voxel-Based Specific Regional Analysis System for Alzheimer’s Disease) is performed using high-resolution MRI scans in combination with specialized voxel-based analysis software. The MRI captures detailed images of the brain, which are then processed by the VSRAD system to analyze specific regions such as the hippocampus, parahippocampal gyrus, and amygdala.

The software compares the patient’s brain images to a database of healthy controls, allowing it to detect and quantify even subtle levels of brain atrophy. The result is a detailed visual and statistical report that highlights any structural changes, providing objective data to assist with clinical evaluation.

1. Consultation and medical history review will be conducted.
2. An MRI brain scan will be performed.
3. The MRI data will be analyzed.
4. The degree of the brain will be assessed and visualized.
5. Results and further recommendations will be provided by the doctor.

<Advantages>
· Detect early signs of Alzheimer’s disease
· Measures brain atrophy
· Provides visual and statistical analysis
· Supports regular monitoring of brain health
· Assists in early diagnosis and intervention
· Safe and non-invasive procedure
· Quick and painless

<Limitations>
· Results may vary depending on image quality and individual condition
· Not suitable for individual with MRI contraindications, such as metal implants and claustrophobia
· May not detect early or subtle cognitive changes

· Refrain from taking caffeine for at least 24 hours before the scan
· Avoid heavy meals for at least 6 hours prior to the scan
· Do not wear any metal jewelry or accessories during the scan

· Avoid strenuous activities for at least 24 hours after the scan
· Avoid anti-inflammatory drugs (NSAIDs) unless cleared by the doctor
· Refrain from drinking alcohol and smoking for at least 24 hours after the treatment

· Pregnant and breastfeeding individuals
· Individuals with severe motion disorders
· Individuals with claustrophobia
· Individuals with metal implants or devices

Q1: What is VSRAD?
A1: VSRAD stands for Voxel-Based Specific Regional Analysis System for Alzheimer’s Disease which analyses brain regions typically affected by Alzheimer’s disease. It helps to detect early stages of Alzheimer.

Q2: Is VSRAD safe?
A2: Yes, VSRAD test is considered safe and it’s non-invasive. It uses MRI technology, which does not involve radiation. However, this treatment is not suitable for patients with implanted pacemakers due to the use of strong magnet in MRI.

Q3: How long does this test take?
A3: VSRAD test typically takes 45 minutes. The duration depends on the specific procedure and patient’s comfort during the scan.

Q4: How accurate is VSRAD test?
A4: The accuracy of VSRAD can vary based on factors such as the stage of Alzheimer’s and individual differences. Research has shown that the test has an accuracy rate of about 94% for patients under 75 years old.

Q5: Are there any risks associated with VSRAD test?
A5: VSRAD test is generally safe and carries minimal risk. However, it is important to consult with the doctor if you have any medical conditions that could increase the risk of complications.

[Clinic Name] Forest of Regeneration Clinic Roppongi (Saisei No Mori Clinic)
[Location] Tokyo, Japan
[Nearest Station/ Nearest Tourist Destination] Clinic is located about 5 mins away from The National Art Center and 9 mins Roppngi Tunnel Wallart
[Clinic Opening Time] Monday - Friday (10:00AM - 3:00PM) ; Saturday (10:00AM - 2:00PM) ; Clinic Closed on Sunday, Public Holidays and every 1st, 3rd and 5th Fridays