Stem Cell Culture Supernatant Therapy (Advanced Regenerative Pain Treatment)

· Those in Tokyo looking to relieve chronic pain without surgery.
· Those who want to delay or avoid joint replacement.
· Those who want to try a minimally invasive regenerative treatment.
· Those who wish to improve joint function and mobility.
· Those who wish to use their own fat-derived cells for therapy.

Stem Cell Culture Supernatant Therapy is a regenerative pain treatment that uses bioactive substances secreted by mesenchymal stem cells (MSCs), typically derived from a patient’s own abdominal fat. Instead of relying only on the stem cells themselves, this therapy utilizes the conditioned medium – culture supernatant – collected during cell cultivation. This supernatant contains growth factors, cytokines, and anti-inflammatory proteins which help to regulate inflammation and support tissue repair. It is commonly used for conditions such as knee osteoarthritis and other chronic inflammatory or degenerative pain disorders.

During Stem Cell Culture Supernatant Therapy, a small amount of fat – about 20 mL – is collected from the abdomen using a minimally invasive syringe technique. The stem cells are isolated and cultured in a sterile laboratory for several weeks, during which they release therapeutic bioactive factors into the culture medium. The purified supernatant is then prepared and injected directly into the affected joint or administered intravenously, depending on the condition being treated. Once administered, these bioactive components help reduce inflammation, modulate immune responses, protect surrounding tissues, and promote the body’s natural healing processes, which may result in reduced pain and improved function over time.

1. Consultation and evaluation will be conducted.
2. Abdominal fat collection will be performed.
3. Stem cell isolation and culture will be conducted.
4. Prepared stem cell therapy will be injected.
5. Post-care instructions will be provided.

<Advantages>
· Enhances natural tissue repair
· Reduces inflammation and pain
· Improves joint mobility and function
· Minimally invasive procedure
· Low risk of allergic reaction
· Utilizes autologous tissue

<Limitations>
· Not suitable for patients with active infection

Q1: How long does it take to see results from Stem Cell Culture Supernatant Therapy?
A1: Most patients begin to notice pain reduction and improved mobility within a few weeks after injection. However, optimal improvement is typically observed between 3 to 6 months.

Q2: How long do Stem Cell Culture Supernatant Therapy results last?
A2: Results vary depending on the severity of the condition, age, and overall health. Many patients experience long-term symptom relief lasting 6 to 12 months or longer.

Q3: Can advanced-stage knee osteoarthritis be treated with Stem Cell Culture Supernatant Therapy?
A3: Some clinical reports suggest that patients with moderate to advanced knee osteoarthritis may still experience pain reduction and functional improvement. However, earlier-stage treatment may produce better outcomes.

Q4: How is the fat collected during Stem Cell Culture Supernatant Therapy?
A4: Approximately 20 mL of abdominal fat is collected using a syringe-based liposuction technique under sterile conditions.

Q5: Are multiple sessions of Stem Cell Culture Supernatant Therapy required?
A5: Some patients may achieve satisfactory results after one session, while others may require multiple injections depending on symptom severity and response to treatment.

[Clinic Name] Kojimachi Dermatology and Plastic Surgery Clinic
[Location] Tokyo, Japan
[Nearest Station/ Nearest Tourist Destination] Easily accessible from Kojimachi, Hanzomon, and Nagatacho Station within 1 to 5 minutes walking distance
[Clinic Opening Time] Monday to Saturday (10:00AM - 1:00PM, 2:00PM - 7:00PM); Closed on Sunday and public holiday

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Customers are advised to contact the healthcare providers directly for any enquiries related to medical treatments.